1.*Takahashi T, Uchibayashi T, Ishii N, Matsuo I, Yoshida Y, Suzuki T. Luminescence detection of peptide:N-glycanase activity using engineered split inteins. Chem. Commun., 58, 13282-13285 (2022)

2.*Takahashi T, Hagiwara H. Detecting ligand-protein interactions inside cells using reactive peptide tags and split luciferase. Chem. Commun., 57, 9906-9909 (2021)

3.Kawase M, Fujioka M, *Takahashi T. Activation of protease and luciferase using engineered Nostoc punctiforme PCC73102 DnaE intein with altered split position. ChemBioChem, 22, 577-584 (2021)

4.Maeda Y, Sawada T, Takahashi T, Yuasa H, *Mihara H. Affinity control of monosaccharide conjugated peptides against lectins with a set of amino acid substitutions on α-helical structures. Bioconjugate Chem., 31, 2533-2540 (2020)

5.*Takahashi T. Generation of active protease depending on peptide-protein interactions using native chemical ligation and protein trans-splicing. Bull. Chem. Soc. Jpn, 92, 1767-1772 (2019)

6.Yamamoto K, Oyaizu M, Takahashi T, Watanabe Y, *Shoji O. Inhibiting aggregation of β-amyloid by folded and unfolded forms of fimbrial protein of gram-negative bacteria. ChemistySelect, 2, 9058-9062 (2017)

7.*Takahashi T, Saito A. Interaction-dependent native chemical ligation and protein trans-splicing (IDNCL-PTS) for detection and visualization of ligand-protein interactions. ChemistySelect, 1, 1768-1772 (2016)

8.*Takahashi T. Construction of sensor protein that responses to amyloid β-peptide oligomers and demonstration of screening capabilities for oligomer inhibitors. Chem. Lett., 44, 67-69 (2015)

9.*Takahashi T, Saito A. Interaction-dependent native chemical ligation and enzyme reconstitution for detection of peptide-peptide interaction. Chem. Lett., 43, 1357-1359 (2014)

10.Okura H, Mihara, H, *Takahashi T. Construction of proteins with molecular recognition capabilities using α3β3 de novo protein scaffolds. Protein Eng. Des. Sel., 26, 705-711 (2013)

11.Murakoshi Y, *Takahashi T, Mihara H. Modification of a small β-barrel protein, to give pseudo-amyloid structures, inhibits amyloid β-peptide aggregation. Chem. Eur. J., 19, 4525-453 (2013)

12.*Takahashi T, Mihara H. FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo–amyloid structure. Chem. Commun., 48, 1568-1570 (2012)

13.Tsutsumi H, Ohkusa H, Park H, Takahashi T, *Mihara H.  Gold nanoparticles conjugated with monosaccharide-modified peptide for lectin detection. Bioorg. Med. Chem. Lett., 22, 6825-6827 (2012)

14.Okura H, Takahashi T, Mihara H. Terminal sequence importance of de novo proteins from binary-patterned library; stable artificial proteins with 11- or 12-amino acid alphabet. Protein. Pept. Lett., 19, 673-679 (2012)

15.Sawada T, Tsuchiya M, Takahashi T, Tsutsumi H, *Mihara H. Cell-adhesive hydrogels composed of peptide nanofibers responsive to biological ions. Polymer J., 44, 651-657 (2012)

16.Furuki T, Shimizu T, Chakrabortee S, Yamakawa K, Hatanaka R, Takahashi T, Kikawada T, Okuda T, Mihara H, Tunnacliffe A, *Sakurai M. Effects of Group 3 LEA protein model peptides on desiccation-induced protein aggregation. Biochem. Biophys. Acta, 1824, 891-897 (2012)

17.Sawada T, Ishiguro K, Takahashi T, *Mihara H. A novel β-loop scaffold of phage-displayed peptides for highly specific affinities. Mol. Biosyst., 7, 2558-2562 (2011)

18.Uozumi R, *Takahashi T, Yamazaki T, Granholm V, Mihara H. Design and conformational analysis of natively folded β-hairpin peptides stabilized by nucleobase interactions. Biopolymers, 94, 830-842 (2010)

19.Shimizu T, Kanamori Y, Furuki T, Kikawada T, Okuda T, Takahashi T, Mihara H, *Sakurai M. Desiccation-induced structuralization and glass formation of group 3 late embryogenesis abund protein model peptides. Biochemistry, 49, 1093-1104 (2010)

20.Suzuki M, Takahashi T, Sato J, Mie M, Kobatake E, *Mihara H. Designed short peptides that form amyloid-like fibrils in coassembly with amyloid β-peptide (Aβ) decrease the toxicity of Aβ to neuronal PC12 cells. ChemBioChem, 11, 1525-1530 (2010) (表紙採用)

21.Miyachi A, Takahashi T, Matsumura S, *Mihara H. Peptide nanofibers modified with a protein by using designed anchor molecules bearing hydrophobic and functional moieties. Chem. Eur. J.,16, 6644-6650 (2010)

22.*Takahashi T, Ohta K, Mihara H. Rational design of amyloid β-peptide (Aβ)-binding proteins: Pseudo-Aβ β-sheet surface presented in green fluorescent protein binds tightly and preferentially to structured Aβ. Proteins, 78, 336-347 (2010)

23.Sawada T, Takahashi T, *Mihara H. Affinity-based screening of peptides recognizing assembly states of self-assembling peptide nanomaterials. J. Am. Chem. Soc., 131, 14434-14441 (2009)

24.*Takahashi T, Tada K, Mihara H. RNA aptamers selected against amyloid β-peptide (Aβ) inhibit the aggregation of Aβ. Mol. Biosyst., 5, 986-991 (2009) (Emerging Investigators Issue)

25.Jumawid MT, *Takahashi T, Yamazaki T, Ashigai H, Mihara H. Selection and structural analysis of de novo proteins from an α3β3 genetic library, Protein Sci., 18, 384-398 (2009)

26.*Takahashi T, Ohta K, Mihara H. Embedding the amyloid β-peptide (Aβ) sequence in green fluorescent protein (GFP) inhibits Aβ oligomerization, ChemBioChem, 8, 985-988 (2007) (表紙採用)

27.Sato J, Takahashi T, Oshima H, Matsumura S, *Mihara H. Design of peptides that form amyloid-like fibrils capturing amyloid β1-42 peptides, Chem. Eur. J., 13, 7745-7752 (2007)

28.Watanabe S, Tomizaki KY, Takahashi T, Usui K, Kajikawa K, *Mihara H. Interactions between peptides containing nucleobase amino acids and T7 phages displaying S. cerevisiae proteins, Biopolymers,  88, 131-140 (2007)

29.*Takahashi T, Dewi Y, Mihara H. Utilization of L-α-nucleobase amino acids (NBAs) as a protein engineering tool: construction of NBA-modified HIV-1 protease analogues and enhancement of dimerization induced by nucleobase interaction, ChemBioChem, 査読有, 7, 729-732 (2006)

30.Gyurcsik B, Haruki H, Takahashi T, Mihara H, *Nagata K. Binding modes of the precursor of Adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the Adenovirus chromatin, Biochemistry, 45, 303-313 (2006)

31.Miyanishi H, *Takahashi T, Mihara H. De novo design of peptides with L-α-nucleobase amino acids and their binding properties to the P22 boxB RNA and its mutants, Bioconjugate Chem., 15, 694-698 (2004)

32.Yana D, Takahashi T, Mihara H, *Ueno A. A peptide-cyclodextrin hybrid system capable of detecting guest molecules utilizing fluorescence resonance energy transfer, Macromol. Rapid Commun., 25, 577-581 (2004)

33.Yamashita T, Takahashi Y, Takahashi T, *Mihara H. Inhibition of peptide amyloid formation by cationic peptides with homologous sequences, Bioorg. Med. Chem. Lett., 13, 4051-4054 (2003)

34.Matsumura S, Takahashi T, Ueno A, *Mihara H. Complementary nucleobase interaction enhances peptide-peptide recognition and self-replicating catalysis, Chem. Eur. J., 9, 4829-4837 (2003)

35.Takahashi T, Ueno A, *Mihara H. Nucleobase amino acids incorporated into the HIV-1 nucleocapsid protein increased the binding affinity and specificity for a hairpin RNA, ChemBioChem, 3, 543-549 (2002) (表紙採用)

36.Balasundaram G, Takahashi T, Ueno A, *Mihara H. Construction of peptide conjugates with peptide nucleic acids containing an anthracene probe and their interactions with DNA, Bioorg. Med. Chem., 9, 1115-1121 (2001)

37.Takahashi T, Hamasaki K, Ueno A, *Mihara H. Construction of peptides with nucleobase amino acids: design and synthesis of the nucleobase-conjugated peptides derived from HIV-1 Rev and their binding properties to HIV-1 RRE RNA, Bioorg. Med. Chem., 9, 991-1000 (2001)

38.Kumagai I, Takahashi T, Hamasaki K, Ueno A, *Mihara H. HIV-1 Rev peptides conjugated with peptide nucleic acids and their efficient binding to RRE RNA, Bioorg. Med. Chem Lett., 11, 1169-1172 (2001)

39.Kuribayashi H, Takahashi T, Nagata K, Ueno A, *Mihara H. Construction of two-stranded α-helix peptides based on influenza virus M1 protein selectively bound to RNA, Bioorg. Med. Chem. Lett., 10, 2227-2230 (2000)

40.Takahashi T, Hamasaki K, Kumagai I, Ueno A, *Mihara H. Design of a nucleobase-conjugated peptide that recognizes HIV-1 RRE IIB RNA with high affinity and specificity, Chem. Commun., 349-350 (2000)

41.Kumagai I, Takahashi T, Hamasaki K, Ueno A, *Mihara H. Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA, Bioorg. Med. Chem. Lett., 10, 377-379 (2000)